Prepare grill for high direct heat cooking. In a bowl, combine ground turkey breadcrumbs, cream, Worcestershire sauce, pepper, garlic powder, salt and cayenne pepper.
Divide mixture into 4 portions and shape into patties. Grill burgers 1 minute on each side; remove from grill.
Lay 1 bacon strip horizontally and 1 bacon strip vertically over top of each burger; weave remaining bacon slice between other bacon slices to form a lattice on burger top; wrap bacon ends under the burger.
Grill 6 to 8 minutes, turning once. Always cook to well-done, 165°F as measured by a meat thermometer.
In a bowl, combine mayonnaise and jalapeno pepper. Spread mayonnaise mixture on cut sides of buns. Place burger on bun bottom and add a dollop of guacamole and cover with bun top.